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            Senior Scientist, William (Bill) C. Kerr, PhD, is Director of ARG’s National Alcohol Research Center and Co-Directs the National Alcohol Survey and the Health Disparities projects.  Bill also serves as the scientific director at ARG and continues to lead R01 projects, including a grant to investigate secondhand harms from alcohol and other drugs.

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            Scientist Nina Mulia, DrPH, is Center Associate Director and Director of the Alcohol Services project. She specializes in and has published widely on race and ethnicity and socioeconomic disparities in heavy drinking, alcohol problems, and alcohol services utilization.

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            This project, led by Camillia Lui, PhD, traces trends in harmful drinking patterns over a 40-year period, and identifies a range of alcohol-related precursors and problems through event-based and population-based approaches to inform early screening and interventions for high-risk groups.

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Role of Health Care in Addressing Unhealthy Alcohol Use and Disparities among Aging Women

Funding: R01AA030297

Principal Investigator: Cynthia Campbell (Kaiser), Co-Investigator: Nina Mulia

This timely study examines trends and predictors of unhealthy alcohol use among aging women (≥ age 50) in a large, diverse health care system, and how health services can reduce unhealthy use, with a particular focus on potential disparities for racial/ethnic minority women. We also interview patients, and providers who care for them, to gain a deeper understanding of aging women’s needs, and potential treatment strategies. Findings will inform how health systems can address unhealthy alcohol use among aging women, a critical growing clinical and public health problem.


Unhealthy alcohol use has increased significantly among aging women, raising their risk of serious alcohol related adverse consequences. At the same time, they are less likely than men to access treatment, and this is exacerbated among racial/ethnic minority women. Health care providers and systems will face an increasing number of aging women with alcohol problems, often with co-occurring health conditions that would improve with reduced drinking.

Currently, there is limited research on the growing needs of this aging population, including on how racial/ethnic minority women may be disproportionately impacted by unhealthy alcohol use and on how to develop effective interventions. To understand these critical gaps and inform a holistic approach to alcohol-related healthcare, we are conducting a mixed-method study of over one million (1,298,009) aging women (≥age 50) in a diverse health care delivery system of over 4.5 million members.

We leverage unique longitudinal electronic health record (EHR) data from a universal alcohol screening program in primary care, with an estimated 784,794 aging women regularly screened for unhealthy alcohol use at multiple primary care visits between 2014-2022. We integrate screening data with a NIAAA-funded alcohol registry that contains medical and psychiatric diagnoses, self-report health behaviors (e.g. tobacco, exercise, interpersonal violence screening), and health service encounters across clinical settings.

Our approach is guided by a conceptual model that incorporates Intersectionality Theory and the Andersen’s Model of Health Services Utilization.

We first identify trends and predictors of unhealthy alcohol use (defined as exceeding guidelines or alcohol use disorder) among aging women overall and by age and race/ethnicity. Second, we test whether health services utilization (e.g., routine primary care visits, brief alcohol interventions, medications, and addiction and/or psychiatry treatment) is associated with reductions in alcohol use over time among all aging women who report unhealthy alcohol use and among subsets with co-occurring health conditions (e.g., chronic pain, depression/anxiety, diabetes and hypertension) and medication use (e.g., opioids).

Across each aim, we examine racial/ethnic differences to identify potential disparities. We use advanced causal modeling approaches to analyze hypothesized relationships, and to appropriately control for potential confounding and biases. For a deeper understanding of these vulnerable patients’ needs and potential barriers to care, we conduct qualitative interviews with aging women who report unhealthy alcohol use and with providers who care for them in different medical settings (e.g. primary care, geriatrics, addiction medicine), which we triangulate with the quantitative data. Findings will provide urgently needed evidence on how health services can impact unhealthy alcohol use, so that health care systems can better identify and treat this vulnerable population through targeted interventions.

Research Team

Nina Mulia, DrPH

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We are a non-profit research organization that seeks to improve public health through deepening our understanding of alcohol and other drug use and investigating innovative approaches to reduce its consequences for individuals, families, and communities.

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